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논문

Identifying geographic areas at risk of rubella epidemics in Japan using seroepidemiological data

등록일자 :

https://doi.org/10.1016/j.ijid.2020.09.1458

  • 저자Hiroshi Nishiura,Ryo Kinoshita,Taishi Kayanoa,이효정
  • 학술지International Journal of Infectious Disease (1201-9712), 102, 203 ~ 211
  • 등재유형SCIE
  • 게재일자 20210101
Objective: Even with relatively high vaccination coverage, Japan experienced rubella epidemics in 2012?2014 and 2018?2019, which were fueled by untraced imported cases. We aimed to develop a risk map for rubella epidemics in Japan by geographic location via analysis of seroepidemiological data and accounting for the abundance of foreign visitors. Methods: Geographic age distribution and seroprevalence were used to compute the age- and sex-dependent next-generation matrix in each region. We computed the probability of a major epidemic using the assumed number of untraced imported rubella cases proportionally modeled to the number of foreign travelers. Results: Risks of a major epidemic were high in areas with capital cities, while areas with a greater fraction of older people yielded smaller effective reproduction numbers, a lower volume of foreign travelers, and thus a lower probability of a major epidemic.

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